The photosensitizing drug in puva is called psoralen. Both the psoralen and the uva light must be administered within one hour of each other for a response to occur. These treatments are usually given in a physician’s office two to three times per week.
The medical treatment does this with the help of a photosensitizing drug and a light source that activates the applied drug, destroying cancer cells. Pdt is approved to treat non-small cell lung cancer, esophageal cancer, and barrett’s esophagus. It treats actinic keratosis, as well as acne, rosacea, skin cancer, sun damage, oily skin, wrinkles, warts, psoriasis, and enlarged sebaceous glands. Puva is a special treatment using a photosensitizing drug and timed artificial-light exposure composed of wavelengths of ultraviolet light in the uva spectrum.
Cardiovascular disease, diabetes, hypertension, inflammatory bowel disease, hyperlipidemia, liver problems, and arthritis are more common in patients with psoriasis. It is very псорилакс for all patients with psoriasis to be carefully monitored by their primary care providers for these associated illnesses.
Common side effects with puva include burning, aging of the skin, increased brown spots called lentigines, and an increased risk of skin cancer, including melanoma. The relative increase in skin cancer risk with puva treatment is controversial. Puva treatments need to be closely monitored by a physician and discontinued when a maximum number of treatments have been reached. Occasionally, a small local injection of steroids directly into a tough or resistant isolated psoriatic plaque may be helpful. It is now apparent that patients with psoriasis are prone to a variety of other disease conditions, so-called comorbidities.
Several weeks of puva is usually required before seeing significant results. The light exposure time is gradually increased during each subsequent treatment. Psoralens may be given orally as a pill or topically as a bath or lotion.
After a short incubation period, the skin is exposed to a special wavelength of ultraviolet light called uva. Patients using puva are generally sun sensitive and must avoid sun exposure for a period of time after puva.